Holly Ross

Research Technologist


The complexity of interactions within the human genome never fails to awe me, yet we still possess tools to begin unraveling the puzzle of how genetic variation can increase an individual’s susceptibility for disease.  I am interested in integrating molecular biology with physiology at the organismal level.   During my undergraduate studies, I enjoyed conducting research in a lab that was investigating a single base substitution that was correlated with increased pancreatic cancer incidence and mortality.  Similarly, our lab studies genetic variations such as how a SNP could create a cascade of events that result in congenital disease.  My role in the laboratory includes assisting in the maintenance of the mouse and zebrafish colonies.  Animals bred to possess a specific genotype can then be utilized in experiments to determine how the disease allele interacts with other genes and to characterize any functional consequences.